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Oxytetracycline
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Oxytetracycline

Oxytetracycline is primarily bacteriostatic and is thought to exert its antimicrobial effect by the inhibition of protein synthesis. Oxytetracycline is active against a wide range of gram-negative and gram-positive organisms. The drugs in the Oxytetracycline class have closely similar antimicrobial spectra, and cross resistance among them is common. Microorganisms may be considered susceptible if the M.I.C. (minimum inhibitory concentration) is not more than 4.0 mcg/ml and intermediate if the M.I.C. is 4.0 to 12.5 mcg/ml. Susceptibility plate testing: A Oxytetracycline disc may be used to determine microbial susceptibility to drugs in the Oxytetracycline class. If the Kirby-Bauer method of disc susceptibility testing is used, a 30 mcg Oxytetracycline disc should give a zone of at least 19 mm when tested against a Oxytetracycline-susceptible bacterial strain. Oxytetracyclines are readily absorbed and are bound to plasma proteins in varying degree. They are concentrated by the liver in the bile, and excreted in the urine and feces at high concentrations and in a biologically active form.

Other names for this medication:
Oxytetracycline, Terramycin, Oxyteracin, Cotet,

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